Rapid Synthesis of Bradykinin in Solution

Two variants of the two-phase-purification method are examined, using the preparation of bradykinin as a model.In one synthesis, intermediate purification by liquid-liquid extraction was carried out 106P1 after each completed elongation, in the other, new variant, the extractions were performed after the deprotection steps.If not hampered by technical difficulties the second variant ELDERBERRY COCKTAIL is more efficient.